Showing posts with label drug. Show all posts
Showing posts with label drug. Show all posts

Thursday, 7 May 2015

An Introduction to Medicinal Chemistry, G. Patrick, Oxford.



A perfect text for university courses on the pharmacology is An Introduction to Medicinal Chemistry, by G. Patrick. It is a complete coverage of the subject with accessible and engaging style of writing, equally appreciated by students and lecturers.
The opening chapters devoted to biochemistry, which is essential to understand the medicinal chemistry basics. Structure and functions of important drugs also covered.
The next thing the author is talking about is interaction of drugs, their interaction with body, reactions and consequences.
A second part of the text devoted to principles and general strategies used to discover and design new forms of drugs.
The end of the book covers specific topics related to medicinal chemistry, like cholinergics and anticholinesterases, etc.
Medicinal Chemistry is a fascinating subject with great potential and the author demonstrates it in his book. The special language of the book is easy to read with the help of glossary.
Special text boxes contain in-depth material. Book describes how concepts applied in real life. In the end of every chapter you will find a section with summary and key points, plus a revision. A section with questions can be find at the end of the chapter, along with the link to Online Resource Centre. All in complex, it helps readers to test their understanding and to improve their skills in molecular modelling.

Thursday, 23 April 2015

A Fresh Look at Drug Approval: Moving Away From Tradition

Overview

Approval of novel drugs is complicated. Drug discovery and further implementation of it to market is a key to innovative medicine and improved medical care. Some difficulties hold up the licensure process and spread of drugs. 

Hematology is extremely important sphere of medicine. That is why its development and implementation of new drugs here has high profile. We know that some diseases are infrequent, with different biologies but morphologically similar. To understand the biology of specific conditions scientists need to investigate the molecular level. 

All these peculiarities result in new but specific forms of treatment and medicines. Sometimes it leads to cure and in some cases to remission. Authors of the book concentrate on stages of drug development. The aim is to provide a reader with a detailed overview of the development process, their validation and monitoring after approval. 

The authors of the book are Dr. Victoria Richon, Dr. Michael Grever and Dr. Mark Crowther. 

Victoria Richon provides an overview of the first step in drugs development. She starts with scientific observation from the basic science lab and moves to clinical trial. She makes an emphasis on rare diseases.  

Dr. Miichael Grever explores licensure and makes an overview of optimal ways of drugs approval.

Dr. Mark Crowther uses real examples and emphasizes on the importance of the period after medicine approval for its further use in clinics and its regulation.